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The aqueous extract of wheatgrass has an inhibitory effect on oral cancer cell line proliferation.
Wheatgrass: Green Blood can Help to Fight Cancer NCBI resources Rucha Diwakar Gore, corresponding author1 Sangeeta Jayant Palaskar,2 and Anirudha Ratnadeep Bartake3 Author information Article notes Copyright and License information Disclaimer Abstract Introduction Oral squamous cell carcinoma is the sixth most common cancer worldwide and is one of the leading causes of death especially in developing countries like India. It is usually managed with the help of chemotherapeutic agents that are toxic not only to the tumor cells but also to normal cells in many ways. Whereas the traditional herbal medicines which are used from ancient days in India are generally known to be free of toxic effects and are effective. Wheatgrass is the young grass of the wheat plant ‘Tritcumaestivum Linn’, family Poaceae (Gramineae). It contains several vitamins, minerals, amino acids, and vital enzymes, these play an important role in the anticancer approach of this herbal product. It is also called ‘green blood’ because of its high content of chlorophyll, which bears a structural similarity to hemoglobin, and this result in a high oxygen supply to all the body tissues. Aim To analyze the effect of the aqueous wheatgrass extract on the Oral Squamous Cell Carcinoma (OSCC) cell line by MTT assay. Materials and Methods ‘KB cell line’ (Mouth Epidermal Carcinoma Cells) was used for the present study. An aqueous extract of wheatgrass was prepared in the institution. The study aimed to assess the effect of the aqueous wheat grass extract on the KB cell line(OSCC) by MTT assay. Results A 41.4% of OSCC cell inhibition was observed at 1000 µg/ml dilution of aqueous wheatgrass extract in 24 hours. Conclusion The aqueous extract of wheatgrass has an inhibitory effect on oral cancer cell line proliferation. Keywords: KB cell line, Oral squamous cell carcinoma, Wheatgrass (Triticumaestivum) Go to Introduction OSCC is the sixth most common cancer worldwide and one of the leading causes of death especially in developing countries like India [1]. Cancer is a hyperproliferative disorder that is usually managed with the help of different chemotherapeutics agents that are toxic, not only to cancer cells but also to normal cells in many ways. In addition, these agents are highly expensive and cannot be used for the prevention of cancer. The traditional herbal medicines which have been used since ancient days in India are generally known to be free of any deleterious effects. They are inexpensive and effective [2,3]. Wheatgrass is the young grass of the common wheat plant (Triticumaestivum Linn., family Poaceae) and it is also known as “green blood” because of its high chlorophyll content, i.e., 70% of its chemical composition. Moreover, it has structural similarity with hemoglobin and thus results in a high oxygen supply to all tissues [3]. Apart from these, it contains antioxidant enzymes superoxide dismutase and cytochrome oxidase that have the potential to convert reactive oxygen species to hydrogen peroxide and an oxygen molecule. It also can inhibit oxidative DNA damage [4]. The anticancer activity of the alcoholic extract of wheatgrass on cervical cancer cell lines has already been studied and the anticancer activity of alcoholic wheatgrass extract is proven [5]. The present need is to develop drugs that can potentially target cancer cells and not normal cells. We have carried out this study to check the inhibitory effect of aqueous wheatgrass extract on the OSCC cell line (KB mouth cell line). This channel has other similar video clips about Wheatgrass Bangalore for Cancer Patients, Green blood therapy, and health food Please check them out: https://www.youtube.com/channel/UCkrN168QpVfiy8vkhaCPysA _________________________ If you were trying to find more info about Wheatgrass Bangalore for Cancer Patients or Green blood therapy did this video help?